A unique screening platform combining high-throughput ex vivo simulation of the gut microbiome and high metabolic coverage for better-informed decision making.
The Colon-on-a-Plate® (CoaP) technology is a high-throughput technology that simulates the colonic microbiome of specific individuals, including healthy and diseased states. The technology enables to assess the impact of all types of test products on composition and functionality of the colonic microbiome, and additionally to study effects on immune markers and gut barrier integrity indirectly. This biorelevant ex vivo simulation has demonstrated in vitro-in vivo correlation, as it was shown to accurately predict direct effects on the colonic microbiota (functionality and composition), as well as indirect effects on the host (immune markers and barrier integrity).
